Monday, December 9, 2013

Blog Post #53 - What Cost 2.7billion dollars in 1991 $$ is costing $500 + ipad and in future drop to around $50?

What is Human Genome project?

Have you ever had blood test? Do you know what they are testing and how they do it? You may not care. Now, you should atleast care about Gene Sequencing. Why?

Answer - Human Genome project
and its implications on your life..coming to a lab near you.

If you were not sleeping in your biology class  (like me!) you would have understood the difference between DNA,RNA and Genes.







Gene Makes up DNA. 
DNA makes up Chromosome.
DNA , genes, and chromosomes -all- are present in the nucleus of the cell.

Every cell has DNA 





and this is how a DNA looks



You might also Know the 23 pairs of Chromosomes in each cell 





Every chromosome has a number except 23rd chromosome - which is denoted by X or Y.


Every gene is made up of chromosome from few hundred to 2 million .




and each human body has 20,000 and 25,000 genes and this is a gene








Why should you learn about Cell, Gene,Chromosome and DNA?

Because it is your body and the government spent 2.7billion to sequence your genes and currently the cost is dropping to $500 + ipad to view the results at least for this Guradian reporter - 
Carole Cadwalladr interesting article check out her observations on Human Genome Project and cost at http://www.theguardian.com/science/2013/jun/08/genome-sequenced


Lots and lots of medical field break thorough are expected from this .


Watch Bill Clinton at http://www.youtube.com/watch?v=Y_8XRkb-wbY



This is video footage of President William Jefferson Clinton  speaking at an event in which it was announced that the first survey of the entire human genome had been completed, along with Dr. Francis Collins and Dr. J. Craig Venter. Prime Minister Tony Blair delivered remarks via satellite telecast. This footage is official public record produced by the White House Television (WHTV) crew, provided by the Clinton Presidential Library.

http://www.genome.gov/11006943



As we go into 21st century (Why is it called 21st century when it is still 2013? - not sure.!) we continue to 


1. Looking Inward - Explore our planet - for now we don't know what is at the core of earth

2. Looking upward/Outward - Explore moon and Mars while satellites are going all over the universe. Planned missions to Jupiter's moon (where there is evidence of ice) and other explorations 
3.Looking Inside humans - which is where the human genome comes into play.

In few short years your Quest/CPL or some lab will charge you $50 with $20 co-pay not covered by insurance or with some obscure words like co-insurance and you will have your genes sequenced and sent back to your doctor and /or your employer or your girlfriend or boyfriend.


Why?


The human genome sequence can help understand if you have genes that might cause cancer  in effect 


helping your girlfriend/boyfriend decide whether she should dump you or getting married (and live happily ever after ) 

or 

your employer deciding to hire you based on human genome sequence just like drug test today 

or 

your Primary care Doctor who genuinely wants to help you  by helping you identify diseases early ( I am sure you are not running/walking 3 times a week or eating healthy but want to live long healthy life like me.. so always be friendly with your doctor!)

The above mentioned 3 instances are mentioned just for fun as no one knows exactly what might happen in the future but here is a fact.


Steve Jobs also had his genome sequenced for $100,000 - it was widely reported in the 


media and now it is even in wikipedia!

What will I do if there is no Wikipedia? What will google do if there is no wikipedia as 


google's answer's engine runs on top of wikipedia!




Happy Gene Sequencing

Sivakumar Manikanteswaran








1 comment:

  1. My guess is DNA sequencing is not going to fore-tell you anything, it is like studying about internal combustion engine to analyze a traffic pattern. If human history is anything to be revered it tells us that within 300 years, humans went from horse carriages to sending remote controlled rover on Mars, which is 34 million miles away. So did DNA change in 300 years? of course not, it takes thousands and millions of years. I still don't understand why people are blowing the DNA horn. All those money are completely waste, probably they need to study epigenetics, that is where the answer is, which basically tells us we can become what we repeatedly do, you could be a Bill Gates's kids or a poor rick-shaw driver kids in India, the capabilities are same. Race/religion/color/country/caste are all just hypothetical for brain growth and nurture.

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